A case of improved quality of life in a patient with inoperable pancreatic cancer after repeated RFA

Radiology Case Reports

article

Nino Toria¹  Nino Kikodze¹  Nona Janikashvili¹  Ia Pantsulaia¹  Malkhaz Mizandari¹  Tinatin Chikovani¹  Nagy Habib¹ 

[1] Department of Immunology, Tbilisi State Medical University

关键词: Unresectable pancreatic cancer;    Percutaneous radiofrequency ablation;    T lymphocytes;    Cytokines;    Immunomodulation;   

DOI  :  10.1016/j.radcr.2022.07.017

学科分类：生物化学工程

来源: University of Washington * Department of Radiology

【 摘 要 】

Radiofrequency ablation (RFA) has widespread popularity due to its immune-modulation effects in many cancers. Optimal settings to apply RFA in pancreatic cancer , in which the advanced stage of the tumor at the diagnosis makes various therapeutic approaches fail, are still demanding. We report the case of a patient with unresectable pancreatic cancer in which 3 repetitive RFA has been applied over a period of 3 months. Results revealed an improvement in the patient's clinical condition associated with the reduced incidence of CD4+CD45RO+ T lymphocytes and declined TGF-β level in serum. The good quality of life and disease-free survival were maintained for the next months. Booster application of RFA procedure might be a promising option to improve the quality of life in pancreatic cancer patients.

【 授权许可】

CC BY|CC BY-NC-ND