Difference in serum magnesium level among patients with stable chronic obstructive pulmonary disease (COPD) and exacerbated COPD

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Sanowara, R.^1 ; Keliat, E.N.^2 ; Abidin, A.^2

Department of Internal Medicine Department, Faculty of Medicine, Universitas Sumatera Utara, RSUP H. Adam Malik, Medan, Indonesia^1

Department of Pulmonology and Allery-Immunology Division, Internal Medicine Department, Faculty of Medicine, Universitas Sumatera Utara, RSUP H. Adam Malik, Medan, Indonesia^2

关键词: Chronic obstructive pulmonary disease;    Cross-sectional study;    Cytokines;    Hypersecretion;    Mann-Whitney;    Small airways;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012151/pdf
DOI  :  10.1088/1755-1315/125/1/012151

来源: IOP

【 摘 要 】

Stable COPD is marked with various degrees of inflammation throughout large and small airways also in the alveoli which cause mucus hypersecretion, narrowing of the airway, and alveoli damage. Exacerbation is an episode of elevated inflammation. The relation between inflammation response and magnesium has been observed with the increase of proinflammation cytokines in magnesium deficiency. A cross-sectional study of 34 patients who came to RSUP H. Adam Malik (17 stable COPD patients and 17 acute exacerbated COPD patients) was conducted to examine serum magnesium level and spirometry in stable condition. Mean serum magnesium level for stable COPD patients group was 2.09 ± 0.11 mEq/L. It was higher than in the exacerbated COPD patients group 1.69 ± 0.27 mEq/L. Mann-Whitney statistical analysis showed a significant difference in magnesium level between stable COPD and exacerbated COPD groups (p