Serum level of IL-6 in liver cirrhosis patients

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Rey, I.^1 ; Effendi-Ys, R.^1 ; Dairi, L.B.^1 ; Siregar, G.A.^1 ; Zain, L.H.^1

Division of Gastroenterohepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, H. Adam Malik General Hospital, Medan, Indonesia^1

关键词: Cross-sectional study;    Cytokines;    Difference values;    General hospitals;    Liver cirrhosis;    Regulatory properties;    Serum levels;    Wide spectrum;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012225/pdf
DOI  :  10.1088/1755-1315/125/1/012225

来源: IOP

【 摘 要 】

Cytokines are polypeptides that have a wide spectrum of inflammatory, metabolic, hematopoietic and immunologic regulatory properties. The liver represents an important site of synthesis and clearance organ for several cytokines. This study aimed to evaluate serum IL-6 in liver cirrhosis with the type of underlying disease, child pugh group and various clinical and laboratory parameter. This cross-sectional study was at Adam Malik General Hospital and Pirngadi General Hospital from July - December 2016. We examine 75 patients with liver cirrhosis. The exclusion criteria were hepatoma, sepsis and renal impairment. There were 28 (37.3%), 8 (10.6%) and 39 (52%) for HBV-positive; HCV-positive and HBV- HCV negative liver cirrhosis patients, respectively were 14 (18.7 %), 15 (20 %) and 46 (61.3%) for Child- Pugh A, B and C respectively. There was no significant difference value of IL-6 between HBV positive, HCV positive, and HBV-HCV negative group (7.7/6.1/10.9). There was no significant difference value of IL-6 between child pugh A, B, and C group (4.2/11.0/7.9).