The Relationship Between the Utilization of Arterial Blood Gas Analysis and Rehospitalization in Heart Failure: A Retrospective Cohort Study

Frontiers in Cardiovascular Medicine

article

Xinyu Zhang¹  Yijun Sun¹  Hui Zhang¹  Huixia Lu¹  Xiaoping Ji¹ 

[1] The Key Laboratory of Cardiovascular Remodeling and Function Research, The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Cheeloo College of Medicine, Qilu Hospital, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Shandong University

关键词: arterial blood gas analysis;    heart failure;    PSM;    IPTW;    rehospitalization;   

DOI  :  10.3389/fcvm.2022.847049

学科分类：地球科学(综合)

来源: Frontiers

【 摘 要 】

Background The most common presentation of decompensated HF is dyspnea, and arterial blood gas analysis is an excellent tool for the decision-making process for most dyspneic patients. However, data on the prognostic value of ABG in HF patients are limited. Herein, a retrospective cohort study was conducted to investigate whether the utilization of arterial blood gas analysis was independently associated with re-hospitalization in patients with heart failure. Methods As a retrospective cohort study, the relevant clinical data of hospitalized patients admitted to Zigong Fourth People's Hospital, Sichuan, China from December 2016 to June 2019 with a diagnosis of HF were analyzed. The re-hospitalization within 6 months and the use of intravenous diuretic, nitrates, inotropes, or vasopressors were compared between patients with and without arterial blood gas analysis. We used a multivariable logistic regression model, propensity score analysis, and an inverse probability-weighting model to ensure the robustness of our findings. Results We included 1,605 patients with heart failure. The overall re-hospitalization rate within 6 months was 38.2%; it was 34.8% and 41.8% for heart failure patients with or without arterial blood gas analysis, respectively. In the inverse probability-weighting model, the use of arterial blood gas analysis was associated with a 26% lower re-hospitalization rate within 6 months. Conclusion The performance of arterial blood gas analysis is associated with a 6-month rehospitalization rate benefit in a general population of heart failure patients. This association warrants further investigation.

【 授权许可】

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