Recent trends in epidemiology of dyslipidemias in India

Indian Heart Journal

Samin K. Sharma¹  Anoop Misra²  Ravinder S. Rao³  Rajeev Gupta³ 

[1] Department of Cardiology, Mount Sinai Hospital and Icahn School of Medicine, New York, USA;Department of Metabolic Diseases, Fortis C-DOC Centre, Chiragh Enclave, New Delhi, India;Department of Preventive Cardiology and Medicine, Eternal Heart Care Centre and Research Institute, Mount Sinai New York Affiliate, Jaipur, India;

关键词: Hypercholesterolemia;    Cholesterol;    Lower middle income countries;    Cardiovascular disease;    Coronary heart disease;    Lipids;   

DOI  :  10.1016/j.ihj.2017.02.020

来源: DOAJ

【 摘 要 】

Dyslipidemia is the most important atherosclerotic risk factor. Review of population based studies in India shows increasing mean total cholesterol levels. Recent studies have reported that high cholesterol is present in 25–30% of urban and 15–20% rural subjects. This prevalence is lower than high-income countries. The most common dyslipidemia in India are borderline high LDL cholesterol, low HDL cholesterol and high triglycerides. Studies have reported that over a 20-year period total cholesterol, LDL cholesterol and triglyceride levels have increased among urban populations. Case-control studies have reported that there is significant association of coronary events with raised apolipoproteinB, total cholesterol, LDL cholesterol and non-HDL cholesterol and inverse association with high apolipoproteinA and HDL cholesterol. Prevalence of suspected familial hypercholesterolemia in urban subjects varies from 1:125 to 1:450. Only limited studies exist regarding lipid abnormalities in children. There is low awareness, treatment and control of hypercholesterolemia in India.

【 授权许可】

Unknown