Comparison of open liver resection and RFA for the treatment of solitary 3–5-cmhepatocellular carcinoma: a retrospective study

BMC Surgery

Liver Surgery Group¹  Wang Wentao²  Yan Lunan²  Li Dajiang³  Lei Jianyong⁴ 

[1] ;Liver Surgery, West China Hospital of Sichuan University;The Medical Department, West China Hospital of Sichuan University;Thyroid and Parathyroid Surgery Center, West China Hospital of Sichuan University;

关键词: Hepatocellular carcinoma;    Liver;    Resection;    Radiofrequency ablation;   

DOI  :  10.1186/s12893-019-0663-9

来源: DOAJ

【 摘 要 】

Abstract Background The goal of this study was to compare the postoperative results of liver resection and radiofrequency ablation (RFA) for the treatment of small hepatocellular carcinoma (HCC) (3–5 cm). Patients and methods We retrospectively collected 122 cases of small solitary HCC treated at our center from Jan 2011 to Dec 2015, with diameters in the range of 3–5 cm. According to the treatment program received at our center, the patients were divided into liver resection (72 patients) and RFA (50 patients) groups. Result In comparison with the RFA group, the resection group had a longer operative time, greater intraoperative blood loss (P < 0.01), more hepatic inflow occlusion, and a longer postoperative hospital stay (P < 0.01). The 1-, 3-, and 5-year expected overall survival rates and tumor-free survival rates were comparable between the two groups. Cox regression analysis showed that neither resection nor RFA was a significant risk factor for overall or tumor-free survival in HCC. Conclusions For solitary HCC of 3–5 cm in diameter, RFA can achieve better in-hospital clinical results and similar long-term outcomes than resection and can be considered for wide application, especially for central-location cases.

【 授权许可】

Unknown