Systematically comparing COVID-19 with the 2009 influenza pandemic for hospitalized patients

International Journal of Infectious Diseases

Qiuwei Pan¹  Zhongren Ma²  Pengfei Li³  Maikel P. Peppelenbosch³  Yining Wang³ 

[1]Corresponding authors at: Biomedical Research Center, Northwest Minzu University, No. 1, Xibei Xincun, Lanzhou, 730030, China.

[2]Biomedical Research Center, Northwest Minzu University, Lanzhou, China

[3]Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Rotterdam, The Netherlands

关键词: COVID-19;    2009 influenza pandemic;    Clinical features;    Symptoms;    Comorbidities;    Meta-analysis;   

DOI  :  

来源: DOAJ

【 摘 要 】

Objectives: This study aimed to comprehensively compare the clinical features of hospitalized COVID-19 patients with hospitalized 2009 influenza pandemic patients. Methods: Medline, Embase, Web of Science, Cochrane CENTRAL, and Google scholar were systematically searched to identify studies related to COVID-19 and the 2009 influenza pandemic. The pooled incidence rates of clinical features were estimated using the DerSimonian-Laird random-effects model with the Freeman-Tukey double arcsine transformation method. Results: The incidence rates of fever, cough, shortness of breath, sore throat, rhinorrhea, myalgia/muscle pain, or vomiting were found to be significantly higher in influenza patients when compared with COVID-19 patients. The incidence rates of comorbidities, including cardiovascular disease/hypertension and diabetes, were significantly higher in COVID-19 compared with influenza patients. In contrast, comorbidities such as asthma, chronic obstructive pulmonary disease, and immunocompromised conditions were significantly more common in influenza compared with COVID-19 patients. Unexpectedly, the estimated rates of intensive care unit admission, treatment with extracorporeal membrane oxygenation, treatment with antibiotics, and fatality were comparable between hospitalized COVID-19 and 2009 influenza pandemic patients. Conclusions: This study comprehensively estimated the differences and similarities of the clinical features and burdens of hospitalized COVID-19 and 2009 influenza pandemic patients. This information will be important to better understand the current COVID-19 pandemic.

【 授权许可】

Unknown