Acute disseminated encephalomyelitis: a case report of effective early immunotherapy

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Ritarwan, K.^1 ; Ramayani, O.R.^2 ; Eyanoer, P.^3

Department of Neurology, Faculty of Medicine, Universitas Sumatera Utara, Jalan Bunga Lau No 17, Kemenangan Tani, Medan Tuntungan

20136, Indonesia^1

Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Jalan Bunga Lau No 17, Kemenangan Tani, Medan Tuntungan

20136, Indonesia^2

Department of Community and Preventive Medicine, Faculty of Medicine, Universitas Sumatera Utara, Jl. Dr. Mansyur No.5, Medan, Indonesia^3

关键词: Adult patients;    Case reports;    Central nervous systems;    Clinical features;    High dose;    Multifocal;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012212/pdf
DOI  :  10.1088/1755-1315/125/1/012212

来源: IOP

【 摘 要 】

Acute disseminated encephalomyelitis (ADEM) is a monophasic acute non-vasculitic inflammatory demyelinating disorder of the central nervous system characterized by diffuse neurologic signs and symptoms coupled with evidence of multifocal lesions of demyelination on neuroimaging. Despite the long-standing recognition of ADEM as a specific entity, no consensus definition of ADEM had been reached until recently. Historically, different definitions of ADEM have been in published cases of pediatric and adult patients, which varied as to whether events required (1) monofocal or multifocal clinical features, (2) a change in mental status, and (3) a documentation of previous infection or immunization. The treatment has been given to the patient such as supportive therapy and high dose corticosteroids.