Acceleration of X-chromosome gene order evolution in the cattle lineage

BMB Reports

关键词: Cattle;    Eutheria;    Evolution;    Gene order;    X chromosome;   

DOI  :  http://dx.doi.org/10.5483/BMBRep.2013.46.6.185

来源: DOAJ

【 摘 要 】

The gene order on the X chromosome of eutherians isgenerally highly conserved, although an increase in the rate ofrearrangement has been reported in the rodent lineage.Conservation of the X chromosome is thought to be caused byselection related to maintenance of dosage compensation.However, we herein reveal that the cattle (Btau4.0) lineage hasexperienced a strong increase in the rate of X-chromosomerearrangement, much stronger than that previously reported forrodents. We also show that this increase is not matched by asimilar increase on the autosomes and cannot be explained byassembly errors. Furthermore, we compared the difference intwo cattle genome assemblies: Btau4.0 and Btau6.0 (Bostaurus UMD3.1). The results showed a discrepancy betweenBtau4.0 and Btau6.0 cattle assembly version data, and webelieve that Btau6.0 cattle assembly version data are not morereliable than Btau4.0. [BMB Reports 2013; 46(6): 310-315]

【 授权许可】

Unknown