Allogeneic Demineralized Dentin Matrix Graft for Guided Bone Regeneration in Dental Implants

Applied Sciences

Na-Hee Chang¹  Yonghoon Choi²  Jeong-Kui Ku³  Pil-Young Yun⁴  Young-Kyun Kim⁴  In-Woong Um⁵  Yu-Mi Kim⁵ 

[1] Biomedical Research Institute, Seoul National University Bundang Hospital, Seongnam 13620, Korea;Department of Conservative Dentistry, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam 13620, Korea;Department of Oral and Maxillofacial Surgery, Section of Dentistry, Armed Forces Capital Hospital, Armed Forces Medical Command, Seongnam 13574, Korea;Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam 13620, Korea;R&D Institute, Korea Tooth Bank, Seoul 03011, Korea;

关键词: allogeneic demineralized dentin matrix;    buccal marginal bone;    demineralized dentin matrix;    dental implant;    guided bone regeneration;   

DOI  :  10.3390/app10134661

来源: DOAJ

【 摘 要 】

Autogenous and allogeneic demineralized dentin matrices (Auto-DDM and Allo-DDM, respectively) are currently used for guided bone regeneration (GBR). Buccal marginal bone (BMB) resorption is critical for successful implant integration. This study analyzed BMB resorption around dental implants for GBR between the control group (Auto-DDM graft) and experimental group (Allo-DDM graft). From 2014 to 2019, we enrolled 96 patients (59 males, 37 females, average 57.13 years) who received GBR (52 and 44 using Allo-DDM and Auto-DDM, respectively,) without a barrier membrane and a simultaneous single dental implantation (54 in the maxilla and 42 in the mandible). BMB height was measured immediately after GBR, at prosthetic loading, and 12 months after loading. BMB resorption was classified as initial resorption (between GBR and prosthetic loading) and functional resorption (during 12 months after prosthetic loading). The differences in the BMB levels of Auto-DDM and Allo-DDM were analyzed between the initial and functional resorption stages by independent sample t-test. Auto-DDM and Allo-DDM showed similar BMB changes in initial resorption (0.73 ± 0.97 and 0.72 ± 0.77 mm, respectively) and functional resorption (0.69 ± 0.81 and 0.48 ± 0.58 mm, respectively) without a significant difference between the maxilla and mandible. For GBR, Allo-DDM is comparable to Auto-DDM in terms of BMB resorption.

【 授权许可】

Unknown