Partition Coefficients (logP) of Hydrolysable Tannins

Molecules

Valtteri Virtanen¹  Maarit Karonen¹ 

[1] Natural Chemistry Research Group, Department of Chemistry, University of Turku, FI-20014 Turku, Finland;

关键词: ellagitannins;    gallic acid derivatives;    gallotannins;    HPLC;    hydrolysable tannins;    hydrophobicity;   

DOI  :  10.3390/molecules25163691

来源: DOAJ

【 摘 要 】

The partition coefficients (logP) between n-octanol and water of 47 purified and characterized hydrolysable tannins were measured with the shake flask method utilizing UPLC and HPLC with UV detection. Results show that galloyl glucoses and gallotannins are clearly more hydrophobic than ellagitannins but the differences in hydrophobicity within ellagitannins are more varied than within galloyl glucoses or gallotannins. Most notable structural features that were found to influence the hydrophobicity of ellagitannins were the number of free galloyl groups, acyclic versus cyclic polyol, substitution of the anomeric position of glucose and ⁴C₁ versus ¹C₄ conformation of the glucopyranose core.

【 授权许可】

Unknown