期刊论文详细信息
Molecules | |
Efficient PPA-SiO2-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions | |
Md. Saiful Islam1  Mughal Qayum2  Umer Rashid3  Ihsan Ali4  Muhammad Nisar4  Muhammad Raza Shah5  Muhammad Zia-Ul-Haq6  | |
[1] Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia;Department of Pharmacy, Kohat University of Science and Technology, Kohat-26000, Pakistan;Institute of Advanced Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia;Institute of Chemical Sciences, University of Peshawar, Peshawar-25120, Pakistan;Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan;The Patent Office, Karachi 74400, Pakistan; | |
关键词: solvent free; 5,5-dimethylcyclohexan-1,3-dione; PPA-SiO2; β-enaminones; | |
DOI : 10.3390/molecules181215182 | |
来源: DOAJ |
【 摘 要 】
An efficient method has been developed for the synthesis of β-enaminones under solvent-free reaction conditions using PPA-SiO2 as catalyst. The reaction yields were good to excellent (up to 90%). This methodology affords high selectivity and good tolerance of a variety of different functional groups present on both aromatic and aliphatic amines. In addition, the methodology is environmentally benign and cost-effective due to absence of solvent and easy work-up.
【 授权许可】
Unknown