期刊论文详细信息
Molecules | |
Efficient PPA-SiO2-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions | |
Muhammad Nisar5  Ihsan Ali5  Muhammad Raza Shah3  Mughal Qayum4  Muhammad Zia-Ul-Haq1  Umer Rashid2  | |
[1] The Patent Office, Karachi 74400, Pakistan; E-Mail:;Institute of Advanced Technology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia;H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan; E-Mail:;Department of Pharmacy, Kohat University of Science and Technology, Kohat-26000, Pakistan;Institute of Chemical Sciences, University of Peshawar, Peshawar-25120, Pakistan; E-Mail: | |
关键词: solvent free; 5; 5-dimethylcyclohexan-1; 3-dione; PPA-SiO2; β-enaminones; | |
DOI : 10.3390/molecules181215182 | |
来源: mdpi | |
【 摘 要 】
An efficient method has been developed for the synthesis of β-enaminones under solvent-free reaction conditions using PPA-SiO2 as catalyst. The reaction yields were good to excellent (up to 90%). This methodology affords high selectivity and good tolerance of a variety of different functional groups present on both aromatic and aliphatic amines. In addition, the methodology is environmentally benign and cost-effective due to absence of solvent and easy work-up.
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190031092ZK.pdf | 349KB | download |