Efficient Synthesis of β-Enaminones and β-Enaminoesters Catalyzed by Gold (I)/Silver (I) under Solvent-Free Conditions

Molecules

Ming Zhang¹  Ablimit Abdukader¹  Yong Fu¹ 

[1] ¹State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China ²School of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, China ³State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

关键词: gold;    solvent-free;    amines;    β-enaminones;    β-enaminoesters;   

DOI  :  10.3390/molecules17032812

来源: mdpi

【 摘 要 】

An efficient method for the synthesis of β-enaminones and β-enaminoesters using a combination of [(PPh₃)AuCl]/AgOTf as catalyst has been developed. The reaction between 1,3-dicarbonyl compounds and primary amines was carried out under solvent-free conditions with low catalyst loading in good to excellent yields at room temperature.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.