期刊论文详细信息
Marine Drugs | |
Briarenolides K and L, New Anti-Inflammatory Briarane Diterpenoids from an Octocoral Briareum sp. (Briareidae) | |
Tzu-Rong Su1  Yin-Di Su2  Jyh-Horng Sheu2  Ping-Jyun Sung2  Zhi-Hong Wen2  Jih-Jung Chen3  Lee-Shing Fang4  Tsong-Long Hwang5  Yang-Chang Wu6  | |
[1] Department of Beauty Science, Meiho University, Pingtung 912, Taiwan;Department of Marine Biotechnology and Resources, Asia-Pacific Ocean Research Center,National Sun Yat-sen University, Kaohsiung 804, Taiwan;Department of Pharmacy, Tajen University, Pingtung 907, Taiwan;Department of Sport, Health and Leisure, Cheng Shiu University, Kaohsiung 833, Taiwan;Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan;School of Pharmacy, College of Pharmacy, China Medical University, Taichung 404, Taiwan; | |
关键词: Briareum; briarane; octocoral; anti-inflammatory; iNOS; | |
DOI : 10.3390/md13021037 | |
来源: DOAJ |
【 摘 要 】
Two new briarane-type diterpenoids, briarenolides K (1) and L (2), were isolated from an octocoral identified as Briareum sp. The structures of new briaranes 1 and 2 were elucidated by spectroscopic methods. In the in vitro anti-inflammatory effects test, briaranes 1 and 2 were found to significantly inhibit the accumulation of the pro-inflammatory iNOS protein of the lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells.
【 授权许可】
Unknown