Evaluation of Pediatric Surgical Site Infections Associated with Colorectal Surgeries at an Academic Children’s Hospital

Healthcare

Rima Bhakta¹  Michele Honeycutt²  Kimberly Pough³  Holly Maples³  Vini Vijayan⁴ 

[1] College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA;Department of Infection Prevention and Hospital Epidemiology, Arkansas Children’s Hospital, Little Rock, AR 72202, USA;Department of Pharmacy Practice, Arkansas Children’s Hospital, Little Rock, AR 72202, USA;Division of Infectious Diseases, Department of Pediatrics, Valley Children’s Hospital, Madera, CA 93636, USA;

关键词: colorectal surgery;    pediatric;    surgical prophylaxis;    antibiotic prophylaxis;    surgical site infections;   

DOI  :  10.3390/healthcare8020091

来源: DOAJ

【 摘 要 】

Appropriate use of antibiotic prophylaxis (AP) is a key measure for the prevention of surgical site infections (SSI) in colorectal surgeries; however, despite the presence of national and international guidelines, compliance with AP recommendations remains low. The purpose of this study is to evaluate compliance with recommendations for the use of AP in children undergoing colorectal surgeries and to evaluate the effectiveness of antibiotics in the prevention of SSI. We collected demographic and clinical characteristics of patients who underwent colorectal surgeries, as well as microbiological and antimicrobial susceptibility data for patients who developed SSI. AP data were collected and compared with national guidelines. Antibiotic dosing and duration were most frequently in concordance with national guidelines, while antibiotic timing and selection had the lowest rates of compliance. Twelve of the 192 colorectal procedures evaluated resulted in SSI. Only 2 of the 12 children with SSI received appropriate AP for all four categories evaluated. Eight cases that resulted in SSI were due to organisms not covered by the recommended AP. We identified multiple areas for the improvement of AP in children undergoing colorectal surgery. A multidisciplinary approach to development of standardized protocols, educational interventions, and EHR-based algorithms may facilitate or improve appropriate AP use.

【 授权许可】

Unknown