A Point Prevalence Survey of Antibiotic Use in 18 Hospitalsin Egypt

Antibiotics

Ghada Ismail¹  Sherine El-Masry¹  Soad Hafez²  Amira Amer²  Mohamad Yehia³  Amani El-Kholy⁴  Gehad A. Abo El-Ata⁴  Maha Talaat⁵  Tamer Saied⁵  Amr Kandeel⁶  Rami Galal⁶  Mohamed Abdel Razik⁷  Ashraf Osman⁷  David P. Calfee⁸ 

[1] Ain Shams University Hospitals, Cairo 11591, Egypt;Alexandria University Hospitals, Alexandria 21111, Egypt;Azhar University Hospitals, Cairo 11517, Egypt;Cairo University Hospitals, Giza 11562, Egypt;Global Disease Detection and Response Center, US Naval Medical Research Unit, No.3,Cairo 11517, Egypt;Ministry of Health and Population, Cairo 11516, Egypt;Minya University Hospitals, Minya 61519, Egypt;Weill Cornell Medical College, New York, NY 10065, USA;

关键词: antibiotic use;    prevalence survey;    surgical prophylaxis;    Egypt;   

DOI  :  10.3390/antibiotics3030450

来源: DOAJ

【 摘 要 】

Inappropriate antibiotic use leads to increased risk of antibiotic resistance and other adverse outcomes. The objectives of the study were to determine the prevalence and characteristics of antibiotic use in Egyptian hospitals to identify opportunities for quality improvement. A point prevalence survey was conducted in 18 hospitals in March 2011.A total of 3408 patients were included and 59% received at least one antibiotic, with the most significant use among persons <12 years and intensive care unit patients (p < 0.05). Third generation cephalosporin were the most commonly prescribed antibiotics (28.7% of prescriptions). Reasons for antibiotic use included treatment of community—(27%) and healthcare-associated infections (11%) and surgical (39%) and medical (23%) prophylaxis. Among surgical prophylaxis recipients, only 28% of evaluable cases received the first dose within two hours before incision and only 25% of cases received surgical prophylaxisfor <24 h. The prevalence of antibiotic use in Egyptian hospitals was high with obvious targets for antimicrobial stewardship activities including provision of antibiotic prescription guidelines and optimization of surgical and medical prophylaxis practices.

【 授权许可】

Unknown