A Point Prevalence Survey of Antibiotic Use in 18 Hospitals in Egypt

Antibiotics

Maha Talaat⁴  Tamer Saied⁴  Amr Kandeel³  Gehad A. Abo El-Ata¹  Amani El-Kholy¹  Soad Hafez²  Ashraf Osman⁵  Mohamed Abdel Razik⁵  Ghada Ismail⁷  Sherine El-Masry⁷  Rami Galal³  Mohamad Yehia⁶  Amira Amer² 

[1] Cairo University Hospitals, Giza 11562, Egypt; E-Mails:;Alexandria University Hospitals, Alexandria 21111, Egypt; E-Mails:;Ministry of Health and Population, Cairo 11516, Egypt; E-Mails:;Global Disease Detection and Response Center, US Naval Medical Research Unit, No.3, Cairo 11517, Egypt; E-Mail:;Minya University Hospitals, Minya 61519, Egypt; E-Mails:;Azhar University Hospitals, Cairo 11517, Egypt; E-Mail:;Ain Shams University Hospitals, Cairo 11591, Egypt; E-Mails:

关键词: antibiotic use;    prevalence survey;    surgical prophylaxis;    Egypt;   

DOI  :  10.3390/antibiotics3030450

来源: mdpi

【 摘 要 】

Inappropriate antibiotic use leads to increased risk of antibiotic resistance and other adverse outcomes. The objectives of the study were to determine the prevalence and characteristics of antibiotic use in Egyptian hospitals to identify opportunities for quality improvement. A point prevalence survey was conducted in 18 hospitals in March 2011. A total of 3408 patients were included and 59% received at least one antibiotic, with the most significant use among persons <12 years and intensive care unit patients (p < 0.05). Third generation cephalosporin were the most commonly prescribed antibiotics (28.7% of prescriptions). Reasons for antibiotic use included treatment of community—(27%) and healthcare-associated infections (11%) and surgical (39%) and medical (23%) prophylaxis. Among surgical prophylaxis recipients, only 28% of evaluable cases received the first dose within two hours before incision and only 25% of cases received surgical prophylaxis for <24 h. The prevalence of antibiotic use in Egyptian hospitals was high with obvious targets for antimicrobial stewardship activities including provision of antibiotic prescription guidelines and optimization of surgical and medical prophylaxis practices.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.