Stem cells and skin regeneration

Folia Histochemica et Cytobiologica

关键词: stem cells;    epidermal stem cells;    VSELs;    CXCR4 receptors;    wound;   

DOI  :  10.5603/9429

来源: DOAJ

【 摘 要 】

Stem cells represent a great hope for regenerative medicine. In adult life, stem cell deposits are kept in organ niches; the need for tissue or organ regeneration mobilizes stem cells via the SDF-1-CXCR4 regulation axis. Constant regeneration of the skin is achieved due to stem cell differentiation within the epidermis and the hair follicle; thus, skin may serve as an excellent source of stem cells. This is of paramount importance in the treatment of chronic skin wounds and burns. (Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 3, pp. 375–380)

【 授权许可】

Unknown