Synthesis, antimicrobial and antioxidant activities of some 5-pyrazolone based Schiff bases

Journal of Saudi Chemical Society

Harshur Jajda¹  Vasudev Thakkar¹  Rikin Patel²  Shashikant Teraiya²  Hitesh Barad²  Narsidas Parmar² 

[1] Department of Biosciences, Sardar Patel University, Vallabh Vidyanagar 388 120, Dist. Anand, Gujarat, India;Department of Chemistry, Sardar Patel University, Vallabh Vidyanagar 388 120, Dist. Anand, Gujarat, India;

关键词: Bisketimine;    Antifungal;    Antibacterial;    Acylation;    FRAP assay;    Monoketimine;    o-, m- & p-Phenylenediamine;   

DOI  :  10.1016/j.jscs.2011.12.014

来源: DOAJ

【 摘 要 】

A series of nine new biologically active Schiff bases 5a–i were synthesized by a condensation of 4-acyl-5-pyrazolones 3a–c with aromatic diamines 4a–d, and characterized by elemental analysis, mass and spectroscopic data. All the compounds showed antibacterial activity against Bacillus subtilis and Escherichia coli, good antifungal activity against Phytophthora infestanse and Aspergillus niger, and ferric-reducing antioxidant power (FRAP).

【 授权许可】

Unknown