Antibacterial Effects of Magnetically-Controlled Ag/Fe3O4 Nanoparticles

Materials

Yi-Ning Chen¹  Weihao Xiao²  Wei-Siou Lin²  Ming Chang³ 

[1] Department of Bioscience Technology, Chung Yuan Christian University, Chung Li 32023, Taiwan;Department of Mechanical Engineering, Chung Yuan Christian University, Chung Li 32023, Taiwan;Key Laboratory of Process Monitoring and System Optimization for Mechanical and Electrical Equipment in Fujian Province, Huaqiao University, Xiamen 361021, China;

关键词: Ag/Fe3O4 nanoparticles;    rotating magnetic field;    Escherichia coli;    antibacterial effect;   

DOI  :  10.3390/ma11050659

来源: DOAJ

【 摘 要 】

This paper presents the use of a magnetic manipulation device to remotely control the movement of Ag/Fe3O4 nanoparticles (NPs) for enhancing the antibacterial effect of Ag particles in aqueous suspensions containing Escherichia coli (E. coli). The Ag/Fe3O4 magnetic NPs were prepared by co-precipitation method where the Ag particles are simultaneously synthesized with the Fe3O4 particles to form Ag and Fe3O4 nanocomposite materials. The manipulation system utilized a homogeneous rotating magnetic field to carry out magnetic stirring of NPs in the petri dishes containing bacterial suspensions. The optimum magnetron parameters and best antibacterial effects were implemented with six different concentrations from 0.6 wt % to 6.6 wt % of the NPs at driving frequencies from 50 rpm to 200 rpm for 3 min. The highest antibacterial effect of 99.4% was achieved at 5.4 wt % of NPs and the driving frequency of 100 rpm. A time-dependent antibacterial effect in 0.1 wt % of Ag/Fe3O4 was also observed. The results indicate that the use of specific rotating magnetic fields to manipulate Ag/Fe3O4 magnetic NPs can significantly improve the antibacterial efficacy. Due to the good biocompatibility of the Ag NPs, the presented technique can be applied to clean water resources in the future.

【 授权许可】

Unknown