Complementarity of Standard Cytogenetic Assays

Bosnian Journal of Basic Medical Sciences

Slavka Ibrulj¹  Anja Haverić²  Sanin Haverić² 

[1] Faculty of Medicine, University of SarajevoInstitute for Genetic Engineering and Biotechnology;Institute for Genetic Engineering and Biotechnology;

关键词: lymphocytes culture;    micronuclei;    chromosome aberrations;   

DOI  :  10.17305/bjbms.2008.2992

来源: DOAJ

【 摘 要 】

Standard cytogenetic assays used in genotoxicology usually include chromosome aberrations analysis and micronucleus cytokinesis-block assay. Both tests originate on standard protocol for lymphocyte culture and can be used as complement or substitute to each other. Aim of this study was to evaluate complementarities between results of chromosome aberration analysis assay and results of micronucleus cytokinesis-block assay in representative sample of inhabitants from Bosnia and Herzegovina. The aim was achieved by calculating Pearson correlation coefficient and simple linear regression.

【 授权许可】

Unknown