The advent of Cytomegalovirus infection in HIV infected patients: A review

Online Journal of Health & Allied Sciences

关键词: Cytomegalovirus infection;    Human immunodeficiency virus;    CMV colitis;    CMV retinitis;    AIDS;   

DOI  :  

来源: DOAJ

【 摘 要 】

Cytomegalovirus is considered as one among the long list of latent infections in humans that although normally controlled by the cellular immune response, gets activated after HIV infection takes its role on infecting the T4 lymphocytes. Clinical disease due to Cytomegalovirus has been recognized in up to 40% of patients with advanced HIV disease. The clinical syndromes most commonly associated include chorioretinitis, esophagitis, colitis, pneumonitis, adrenalitis and neurological disorders. Cytomegalovirus infections are usually diagnosed clinically and by serological tests for CMV immunoglobulin. Chemotherapy using systemic agents, including ganciclovir, intravenous foscarnet and intravenous cidofovir is effective. New agents, as for example an anti-sense agent against cytomegalovirus, appear promising.

【 授权许可】

Unknown