Nanowire-Based Biosensors: From Growth to Applications

Micromachines

Dong-il(Dan) Cho¹  Sangmin Lee²  Kyo-in Koo³  Zongjie Wang⁴  Hyuongho Ko⁵  Keekyoung Kim⁶  Pranav Ambhorkar⁶ 

[1] ASRI/ISRC, Department of Electrical and Computer Engineering, Seoul National University, Seoul 08826, Korea;Department of Biomedical Engineering, Kyung Hee University, Yongin 17104, Korea;Department of Biomedical Engineering, University of Ulsan, Ulsan 44610, Korea;Department of Electrical and Computer Engineering, Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON M5S 3M2, Canada;Department of Electronics, Chungnam National University, Daejeon 34134, Korea;School of Engineering, University of British Columbia, Kelowna, BC V1V 1V7, Canada;

关键词: nanowire;    sensor;    biological applications;    medical applications;    nanomaterial;   

DOI  :  10.3390/mi9120679

来源: DOAJ

【 摘 要 】

Over the past decade, synthesized nanomaterials, such as carbon nanotube, nanoparticle, quantum dot, and nanowire, have already made breakthroughs in various fields, including biomedical sensors. Enormous surface area-to-volume ratio of the nanomaterials increases sensitivity dramatically compared with macro-sized material. Herein we present a comprehensive review about the working principle and fabrication process of nanowire sensor. Moreover, its applications for the detection of biomarker, virus, and DNA, as well as for drug discovery, are reviewed. Recent advances including self-powering, reusability, sensitivity in high ionic strength solvent, and long-term stability are surveyed and highlighted as well. Nanowire is expected to lead significant improvement of biomedical sensor in the near future.

【 授权许可】

Unknown