Challenges to antimicrobial susceptibility testing of plant-derived polyphenolic compounds

Arhiv za Higijenu Rada i Toksikologiju

Knežević Samira¹  Bubonja-Šonje Marina²  Abram Maja² 

[1] Clinic for Infectious Diseases, Clinical Hospital Centre Rijeka,Rijeka, Croatia;Department of Microbiology and Parasitology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia;

关键词: antibiogram;    ast;    plant-derived compounds;    polyphenols;    standardisation;    antibiogram;    ispitivanje antimikrobne osjetljivosti;    prirodni spojevi biljnoga podrijetla;    standardizacija;   

DOI  :  10.2478/aiht-2020-71-3396

来源: DOAJ

【 摘 要 】

As multidrug resistance gains momentum, the last two decades have seen an ever-growing interest in the antimicrobial properties of plant extracts and plant-derived compounds. Most of the focus is on polyphenols – a large and diverse group of phytochemicals with strong antibacterial activity. Testing methods provide reliable results as long as they follow standard procedures. However, methods and procedures used in antimicrobial susceptibility testing (AST) are often too diverse to allow comparison of results. The lack of uniformity and comparability is much owed to the absence of guidelines. The focus of this review is to give a critical overview of different methods used in the assessment of polyphenols antimicrobial efficacy and to highlight the importance of their standardisation.

【 授权许可】

Unknown