期刊论文详细信息
| Pharmaceuticals | |
| The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists | |
| 关键词: GPR35; benserazide; catechol; pyrogallol; | |
| DOI : 10.3390/ph6040500 | |
| 来源: DOAJ | |
【 摘 要 】
Nearly 1% of all clinically used drugs are catecholics, a family of catechol-containing compounds. Using label-free dynamic mass redistribution and Tango β-arrestin translocation assays, we show that several catecholics, including benserazide, catechol, 3-methoxycatechol, pyrogallol, (+)-taxifolin and fenoldopam, display agonistic activity against GPR35.
【 授权许可】
Unknown
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