期刊论文详细信息
Pharmaceuticals | |
The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists | |
Huayun Deng1  | |
[1] Biochemical Technologies, Science and Technology Division, Corning Inc., Corning, NY 14831, USA; E-Mail | |
关键词: GPR35; benserazide; catechol; pyrogallol; | |
DOI : 10.3390/ph6040500 | |
来源: mdpi | |
【 摘 要 】
Nearly 1% of all clinically used drugs are catecholics, a family of catechol-containing compounds. Using label-free dynamic mass redistribution and Tango β-arrestin translocation assays, we show that several catecholics, including benserazide, catechol, 3-methoxycatechol, pyrogallol, (+)-taxifolin and fenoldopam, display agonistic activity against GPR35.
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190037209ZK.pdf | 938KB | download |