Phytochemical screening and inhibitory activity of oxalocalcic crystallization of Arbutus unedo L. leaves

Heliyon

Tarik Sqalli Houssaini¹  Youssef Miyah²  Radouane El Habbani³  Rabie Kachkoul⁴  Anissa Lahrichi⁴  Mohamed Mohim⁴ 

[1] Corresponding author.;Laboratory of Molecular Bases in Human Pathology and Therapeutic Tools, Faculty of Medicine and Pharmacy, University Sidi Mohammed Ben Abdellah, BP 1893, Km 22, Road of Sidi Harazem, Fez, Morocco;Department of Nephrology, University Hospital Hassan II, BP 1835, Atlas, Road of Sidi Harazem, Fez, Morocco;Laboratory of Biochemistry, Faculty of Medicine and Pharmacy, University Sidi Mohammed Ben Abdellah, BP 1893, Km 22, Road of Sidi Harazem, Fez, Morocco;

关键词: Biochemistry;    Pharmaceutical science;    Plant biology;   

DOI  :  

来源: DOAJ

【 摘 要 】

The present study is focused on the experimental verification of the efficiency of Arbutus unedo L. leaves against the crystallization of calcium oxalate. The inhibition of crystallization has been studied in vitro with the absence and the presence of the different concentrations of the infusion and hydroalcoholic extract of the plant. This study consists of measuring, using a UV-Visible spectrophotometer, the temporal evolution of the optical density at λ = 620 nm corresponding to the crystals formation. The latter have been characterized by microscopic observation using an optical microscope, and by Fourier Transform Infrared Spectroscopy (FT-IR). The results suggest a greater effectiveness of the plant infusion with respect to the hydroalcoholic extract against crystallization or nucleation at percentages of 69.41 ± 0.24 or 19.76 ± 0.27% and at 93.92 ± 2.61 and 45.16 ± 3.06% against the aggregation, for both the infusion and the hydroalcoholic extract respectively. A. unedo leaves is a very promising and effective remedy against the crystallization of calcium oxalate and especially in the aggregation stage.

【 授权许可】

Unknown