Investigation of THz Absorptive Signatures in Opioids

Applied Sciences

Alexei Bykhovski¹  Weidong Zhang²  Elliott R. Brown² 

[1] Department of Electrical and Computer Engineering, NC State University, Raleigh, NC 27695, USA;Departments of Physics and Electrical Engineering, Wright State University, Dayton, OH 45435, USA;

关键词: sensing;    opioids;    fentanyl;    oxycodone;    molecular dynamics modeling;    spectroscopy;   

DOI  :  10.3390/app12010061

来源: DOAJ

【 摘 要 】

We investigate the possibility of sensing opioid drugs, such as fentanyl, by their THz electromagnetic signatures. The methods include both computer modeling and experiments. Molecular dynamics simulations predict that fentanyl should display THz resonances, with several of them occurring below 1.0 THz; the lowest one is at around 0.337 THz (337 GHz). Spectroscopy measurements were conducted on oxycodone, which was used as a surrogate for fentanyl. They display vibrational absorption resonances between ∼1.4 and 1.6 THz.

【 授权许可】

Unknown