Evaluation of antibacterial effect of silver nanoparticles paste with and without curcumin as intracanal medication

Bulletin of the National Research Centre

Soha Adel Abdou¹  Amira Ibrahim Mohamed² 

[1] Dental Department, Research Institute of Ophthalmology RIO, Ministry of Scientific Research, Cairo, Egypt;Restorative and Dental Materials Department, National Research Centre, Cairo, Egypt;

关键词: Intracanal medication;    Enterococcus faecalis;    Curcumin;    Silver nanoparticles;    Calcium hydroxide;   

DOI  :  10.1186/s42269-022-00723-1

来源: Springer

【 摘 要 】

BackgroundThe purpose of the current study was to compare the antibacterial activity of silver nanoparticles AgNPs paste and silver nanoparticles AgNPs with curcumin paste as intracanal medications versus calcium hydroxide Ca(OH)2 paste. Thirty extracted, human teeth with single roots were decoronated and mechanically prepared. After sterilization, roots were inoculated with Enterococcus faecalis for 10 days. Roots were separated into three groups in accordance to kind of intracanal medications used; Group A, silver nanoparticles AgNPs (Nanogate company, Cairo, Egypt). Group B, silver nanoparticles AgNPs with curcumin (Nanogate company, Cairo, Egypt). Group C, calcium hydroxide Ca(OH)2 (Metapaste, META BIOMED). First microbiological samples (S1) were collected from the canal, before insertion of intracanal medication. Intracanal medications were kept in root canals in all groups for 7 days; then second microbiological samples (S2) were collected from the canals after medicament removal. After the colony forming units CFUs have been counted, the data were statistically analyzed.ResultsIn the three tested groups, the highest bacterial count was found in (S1), while the least bacterial count was found in (S2) with statistical significant difference between them.ConclusionsThe effect of AgNPs paste and AgNPs with curcumin paste was superior to Ca(OH)2 paste. AgNPs with curcumin paste had the best antibacterial effect.

【 授权许可】

CC BY