Poly (ADP‐ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α‐synuclein degradation via transcription factor EB‐dependent autophagy in mutant α‐synucleinA53T model of Parkinson's disease

Aging Cell

Kanmin Mao¹  Jialong Chen¹  Xian Wu¹  Fei Zou¹  Yue Wen¹  Honglin Yu¹  Huihui Li¹  Yixian Ren¹  Wenjun Li¹ 

[1] Department of Occupational Health and Occupational Medicine, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China;

关键词: autophagy;    Parkinson's disease;    PARP1;    SIRT1;    TFEB;   

DOI  :  10.1111/acel.13163

来源: Wiley

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