CDK2 phosphorylation of Werner protein (WRN) contributes to WRN’s DNA double‐strand break repair pathway choice

Aging Cell

Jong‐Hyuk Lee¹  Raghavendra A. Shamanna¹  Tomasz Kulikowicz¹  Louise S. Christiansen¹  Deborah L. Croteau¹  Nima Borhan Fakouri¹  Edward W. Kim¹  Vilhelm A. Bohr² 

[1] Section on DNA Repair, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA;Section on DNA Repair, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA;Danish Center for Healthy Aging, University of Copenhagen, Copenhagen, Denmark;

关键词: aging;    DNA double strand break;    DNA repair;    phosphorylation;    Werner Syndrome;   

DOI  :  10.1111/acel.13484

来源: Wiley

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