Biomolecules | |
Hsp90: A New Player in DNA Repair? | |
Rosa Pennisi2  Paolo Ascenzi2  Alessandra di Masi2  Thomas Helleday1  Wolf-Dietrich Heyer1  | |
[1] Department of Sciences, Roma Tre University, Viale Guglielmo Marconi 446, Roma I-00146, Italy;;Department of Sciences, Roma Tre University, Viale Guglielmo Marconi 446, Roma I-00146, Italy; E-Mails: | |
关键词: base excision repair; DNA damage response; DNA double strand break; DNA repair; Hsp90; Hsp90 inhibitors; mismatch repair; translation synthesis; | |
DOI : 10.3390/biom5042589 | |
来源: mdpi | |
【 摘 要 】
Heat shock protein 90 (Hsp90) is an evolutionary conserved molecular chaperone that, together with Hsp70 and co-chaperones makes up the Hsp90 chaperone machinery, stabilizing and activating more than 200 proteins, involved in protein homeostasis (
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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