Mechanisms underlying the adaptive response against spontaneous neoplastic transformation induced by low doses of low LET radiation - Final Technical Report

John Leslie Redpath

关键词: ANTIOXIDANTS;    DNA REPAIR;    IN VITRO;    RADIATIONS;    TRANSFORMATIONS low dose low-LET radiation;    radiation-induced neoplastic transformation;    DNA repair;    antioxidants;   

DOI  :  10.2172/897550
RP-ID  :  1
PID  :  OSTI ID: 897550
Others  :  TRN: US200717%%465

学科分类：生物科学（综合）

美国|英语

来源: SciTech Connect

【 摘 要 】

The objective of the research was to examine mechanisms underlying the suppressive effects of low doses (<10 cGy) of low-LET radiation on the endpoint of neoplastic transformation in vitro. The findings indicated a role for upregulation of DNA repair but not of antioxidants.