[DMImd-DMP]: A highly efficient and reusable catalyst for the synthesis of 4H-benzo[b]pyran derivatives

Heterocyclic communications

article

Mohamed Abdenour Redouane¹  Naima Khiri-Meribout¹  Saida Benzerka¹  Abdelmadjid Debache¹ 

[1] Laboratory of Synthesis of Molecules with Biological Interest, Mentouri-Constantine 1 University

关键词: multicomponent reaction;    one-pot synthesis;    pyrano[2;    3-c]pyrazoles;    tetrahydrobenzo[b]pyrans;    ionic liquids;    [DMImd-DMP];   

DOI  :  10.1515/hc-2019-0025

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

A series of substituted 4 H -pyrans derivatives were synthesized by a one-pot, multi-component reaction of aromatic aldehydes, malononitrile, and pyrazolone derivatives or active methylene carbonyl compounds such as dimedone, in the presence of 1,3-dimethyl imidazolium dimethyl phosphate [DMImd-DMP] as a catalyst in aqueous ethanol. Recyclability of the catalyst, high yields, simple product isolation and high atom economy are the noteworthy aspects of this protocol.

【 授权许可】

CC BY|CC BY-NC-ND