Fabrication of atomic force microscope spherical tips and its application in determining the mechanical property of cancer cells

Micro & nano letters

article

Yimin Han¹  Jinghe Wang²  Kui Wang²  Shen Dong² 

[1] Department of Gynaecology, No. 3 Subsidiary Hospital, Harbin Medical University;Center for Precision Engineering, Harbin Institute of Technology

关键词: atomic force microscopy;    cancer;    lung;    cellular biophysics;    nanoindentation;    mechanical testing;    biomechanics;    Young's modulus;    viscoelasticity;    stress relaxation;    elastic constants;    carbon nanotubes;    calibration;    cantilevers;    adhesion;    atomic force microscope spherical tips;    mechanical properties;    cancer metastasis;    atomic force microscopy-based nanoindentation;    AFM tip;    microsphere;    tip apex;    carbon nanotube bundles;    adherence;    elastic constant;    cantilever;    calibration;    Cleveland method;    nanoindentation tests;    lung cancer cells;    Anip-973;    AGZY-83a;    Hertz contact equation;    stress relaxation model;    Young's modulus;    viscoelastic properties;    temperature 37 degC;   

DOI  :  10.1049/mnl.2016.0319

学科分类：计算机科学（综合）

来源: Wiley

【 摘 要 】

bstetrical emergencies are important concerns and need immediate diagnosis and intervention to save the life of mother and fetus. These include obstetrical hemorrhage both ante partum and postpartum, ectopic pregnancy, preeclampsia and other conditions where radiologist, obstetricians, anesthesiologist and ICU team have important role to play. Radiologist play key role in diagnosing emergencies with the use of imaging modalities, though bed side ultrasonography has now become valuable tool in the hands of anesthesiologists as well, in diagnosing various emergencies. The role of interventional radiologist in cases of obstetric hemorrhage is worthwhile especially in postpartum hemorrhage where embolization can be minimally invasive lifesaving procedure. The aim of this article is to discuss the valuable role that the radiologists play with obstetricians and anesthesiologists in the management of these obstetric and emergencies.

【 授权许可】

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