Influence of weight status on bone mineral content measured by DXA in children

BMC Pediatrics

Ernesto Cortes Castell¹  Mercedes Juste Ruiz¹  José Antonio Quesada Rico¹  Francisco Carratalá Marco²  Ana Pilar Nso Roca²  Francisco Sánchez Ferrer² 

[1] Medical School, University of Miguel Hernández de Elche, Sant Joan d’Alacant, Spain;Medical School, University of Miguel Hernández de Elche, Sant Joan d’Alacant, Spain;Hospital Universitario de San Juan de Alicante, Ctra N-332, s/n, 03550, Sant Joan d’Alacant, Alicante, Spain;

关键词: Obesity;    Bone mineral content;    Bone mineral density;    Densitometry;    Weight status;    Osteoporosis;   

DOI  :  10.1186/s12887-021-02665-5

来源: Springer

【 摘 要 】

IntroductionChildhood obesity is a public health problem with repercussions in later life. As tissue formation peaks in childhood we determined how weight status influences bone mineral content.Material and methodsWe studied 553 children aged 4–18 years over 10 years (46.8% girls). We measured age, weight, height and through bone densitometry (DXA), bone mineral content (BMC), bone mineral density (BMD), and waist, arm and hip circumferences. The patients were divided into groups using the body mass index z-score: underweight, normal weight, overweight, obese and very obese.ResultsBMC and BMD values were highest in the normal-weight and overweight groups. Logistic regression showed bone mineralization was inversely associated with waist circumference, the association being positive for weight and age. No differences were found according to sex.DiscussionStudies of the relationship between weight and bone mineralization report contradictory results, often because of different study designs. Moreover, studies in children are either few or with small samples. Our findings in a large sample show the importance of weight status in bone mineralization given the risk of bone fractures or osteoporosis.ConclusionsWeight status influenced bone mineralization. BMC and BMD decreased in children with a higher degree of obesity. Waist circumference correlated negatively with bone mineralization.

【 授权许可】

CC BY