Infections after liver transplantation in adults: data from a university hospital in southern Brazil (1996-2000)

Arquivos de Gastroenterologia

Mônica Vinhas De Souza²  Afonso Luis Barth¹  Mário Reis Álvares-da-silva¹  Adão Rogério Leal Machado¹ 

[1] ,UFRGS Hospital de Clínicas de Porto Alegre Emergency UnitPorto Alegre RS ,Brazil

关键词: Liver transplantation;    Infection;    Risk factors;    Immunocompromised host;    Transplante de fígado;    Infecção;    Fatores de risco;    Hospedeiro imunocomprometido;   

DOI  :  10.1590/S0004-28032007000200008

来源: SciELO

【 摘 要 】

BACKGROUND: Infections after liver transplantations are the most important cause of morbi-mortality. In this study, we assessed the main characteristics of these infections in a southern Brazilian university hospital. METHODS: We conducted a retrospective cohort with 55 patients who underwent orthotopic liver transplantation between 1996 and 2000 in the "Hospital de Clínicas de Porto Alegre", Porto Alegre, RS, Brazil, to characterize the infections that occurred in the group. RESULTS: One or more infections (average 2.10) were diagnosed in 47 patients, especially during the first month after transplantation. The most common were bacteremia, intra-abdominal infections and pneumonia, predominantly with bacteria, especially Staphylococcus sp (and particularly S. aureus) and E. coli. The mortality rate attributed to infections was high: 17 cases of all deaths (total 27 deaths). Significant risk factors for infections included reoperation, diabetes, biliary stenosis and higher Child-Pugh scores. CONCLUSION: Infections remain a severe threat in liver transplant patients, and special efforts should be made to prevent and manage them correctly.

【 授权许可】

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