Contrast induced nephropathy in hypertensive patients after elective percutaneous coronary intervention

3rd International Conference on Biological Sciences and Biotechnology

Andra, Cut Aryfa^1 ; Khairul, Andi^1 ; Arina, Cut Aria^2 ; Mukhtar, Zulfikri^1 ; Nyak Kaoy, Isfanuddin^1

Department of Cardiology, University of Sumatera Utara, Jl. Dr. Mansur Kampus, USU, Medan

20155, Indonesia^1

Department of Neurology, University of Sumatera Utara, Jl. Dr. Mansur Kampus, USU, Medan

20155, Indonesia^2

关键词: complications;    Coronary angiography;    High blood pressures;    Hypertensive patients;    Nephropathy;    Percutaneous coronary intervention;    Renal failure;    Risk factors;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/130/1/012006/pdf
DOI  :  10.1088/1755-1315/130/1/012006

来源: IOP

【 摘 要 】

Contrast induced nephropathy (CIN) is the third lead cause of hospital acquired renal failure and was associated with significant morbidity and mortality. We hypothesized that hypertension is an independent risk factor for the development of CIN in patients undergoing elective percutaneous coronary intervention (PCI). The case-control method was used, 138 patients scheduled for elective PCI. We measured serum creatinine at baseline and after 24 hours of the procedure. CIN was defined as arising in serum creatinine of at least 44 μmol/l (0,5 mg/dl) or 25% rise from baseline. All patients received low osmolality nonionic contrast during PCI. Hypertension was defined as self-reported a history of treated or untreated diagnosed high blood pressure. One hundred thirty-eight patients (74,6%) were male, and 35 patients (25,4%) were female. Among the 138 patients, 86 (62,3%) were hypertensive patients whereas 52 (37,7%) were nonhypertensive patients. There was no difference in baseline serum creatinine levels and the amount of contrast media in patient with and without CIN. CIN developed in 42 patients, 39 patients (92,9%) were hypertensive compared to 3 patients (7,1%) without hypertension with p value