Rosai-Dorfman disease with spontaneous resolution: case report of a child

Revista Brasileira de Hematologia e Hemoterapia

Felipe Barbosa Lima²  Pedro Samuel De Valões Barcelos²  Ana Paula Nunes Constâncio¹  Cleto Dantas Nogueira¹  Antônio Aldo Melo-filho¹ 

[1] ,Universidade Federal do CearáFortaleza CE ,Brazil

关键词: Histiocytosis;    sinus;    Histiocytosis;    non-Langerhans-cell;    Lymphatic diseases;    Lymph;   

DOI  :  10.5581/1516-8484.20110083

来源: SciELO

【 摘 要 】

Rosai-Dorfman disease is a self-limiting condition caused by histiocyte proliferation within the sinusoids of lymph nodes and in extranodal tissue. It is a rare disease, particularly in children, that progresses with extensive lymphadenopathy. This paper reports on the case of a 2-year-old child with progressive cervical lymphadenopathy associated with persistent fever and radiological findings suggestive of lymphoma. Histopathological and immunohistochemistry studies of a lymph node biopsy established the diagnosis of Rosai-Dorfman disease. Both lymphadenopathy and fever resolved spontaneously.

【 授权许可】

CC BY-NC-ND   
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