Generalized eruptive histiocytoma: a rare disease in an elderly patient*

Anais Brasileiros de Dermatologia

Fernanda Cardoso¹  Natália Battisti Serafini¹  Brisa Dondoni Reis¹  Mónica Daniela Gauto Nuñez¹  José Augusto Da Costa Nery¹  Omar Lupi¹ 

关键词: Histiocytoma;    Histiocytosis;    Histiocytosis;    non-Langerhans-cell;    Histiocitoma;    Histiocitose;    Histiocitose de células não Langerhans;   

DOI  :  10.1590/S0365-05962013000100015

来源: SciELO

【 摘 要 】

Generalized eruptive histiocytoma is considered an extremely rare subtype of non-Langerhans cells histiocytosis. In the literature, there are few reports of this disease that mainly affects adults. In this report, we present a case of generalized eruptive histiocytoma in an elderly patient who had presented symptoms for over two months. Multiple erythematous papules, asymptomatic and symmetrically distributed were observed on the trunk and limbs. Histological examination showed a dense mononuclear cell dermal infiltrate. In the immunohistochemical analysis, the cells were CD68 positive, but CD1a, S100 and CD34 negative. A diagnosis of generalized eruptive histiocytoma was established. The aim of our paper is to report a case of a very rare disease, whose subtype and affected age group are even more unusual.

【 授权许可】

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