Splenic and portal vein thrombosis following laparoscopic splenectomy in a pediatric patient with chronic myeloid leukemia

Sao Paulo Medical Journal

Henrique Manoel Lederman¹  Evan Fieldston¹ 

[1] ,The Children's Hospital of Philadelphia Pennsylvania ,United States

关键词: Splenectomy;    Chronic myeloid leukemia;    Magnetic resonance spectroscopy;    Myeloid leukemia;    Esplenectomia;    Leucemia miéloide crônica;    Ressonância magnética;    Leucemia mielóide;   

DOI  :  10.1590/S1516-31802006000500008

来源: SciELO

【 摘 要 】

CONTEXT: Splenic or portal vein thrombosis is a rare complication following splenectomy. CASE REPORT: We report a case of splenic and portal venous thrombosis in a 10-year-old girl with chronic myeloid leukemia who underwent laparoscopic splenectomy prior to bone marrow transplant. Clinical suspicion of such thrombosis should be high for patients who have had splenectomy. The diagnosis is confirmed by Doppler ultrasound or contrast-enhanced computed tomography; magnetic resonance imaging magnetic resonance angiography or arteriography can also be used. Proposals for postoperative screening protocols are discussed. Patients with primary myeloproliferative disorders are at increased risk of portal vein thrombosis, independent of surgical intervention, perhaps due to platelet dysfunction resulting from abnormalities of pluripotent stem cells. Marked splenomegaly (with larger draining veins) is thought to increase the risk of thrombosis.

【 授权许可】

CC BY   
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