Synthesis and characterization of a linker for primary amines used in the solid phase organic synthesis of spermidine

Journal of the Brazilian Chemical Society

Emerson T. Da Silva²  Rosane A. S. San Gil²  Stefano Caldarelli¹  Fabio Ziarelli¹  Edson L. S. Lima² 

[1] ,Universidade Federal do Rio de Janeiro Instituto de Química Rio de Janeiro RJ ,Brazil

关键词: polyamines;    13C CPMAS NMR;    HRMAS NMR;    solid phase organic synthesis;    spermidine;   

DOI  :  10.1590/S0103-50532011000100011

来源: SciELO

【 摘 要 】

A linker resin for the synthesis of functionalized spermidine in good yield is described, along with its characterization by infrared (IR), 13C solid-state nuclear magnetic resonance with cross polarization and magic angle spinning (13C CPMAS NMR) and ¹H high resolution magic angle spinning nuclear magnetic resonance (¹H HRMAS NMR. This linker has been regenerated after cleavage of spermidine and re-used without loss of efficiency.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License