An efficient monitoring technique for solid-phase reactions by KBr pellets/FT-IR using methyl p-aminobenzoate synthesis assisted by microwave radiation on merrifield resin

Journal of the Brazilian Chemical Society

Eifler-Lima, Vera Lucia¹  Graebin, Cedric Stephan¹  Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil¹  Antonow, Dyeison¹ 

关键词: Merrifield resin;    infrared spectroscopy;    solid phase organic synthesis;    microwave-assisted reactions;   

DOI  :  10.1590/S0103-50532004000500028

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The use of KBr pellets in infrared spectroscopy has been investigated for monitoring solid-phase reactions. Synthesis of the methyl p-aminobenzoate on Merrifield resin (MR) is described as a model for this technique, which allows the progress of its three on-bead reaction steps to be monitored throughout their duration.

【 授权许可】

Unknown