Microwave-Assisted One-Pot Synthesis of Pyrazolone Derivatives under Solvent-Free Conditions

Molecules

Ruoqun Ma¹  Jin Zhu¹  Jie Liu¹  Lili Chen¹  Xu Shen¹  Hualiang Jiang¹ 

[1] ¹School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China

关键词: microwave-assisted reactions;    one-pot;    pyrazolones;   

DOI  :  10.3390/molecules15053593

来源: mdpi

【 摘 要 】

An efficient one-pot method to generate structurally diverse and medicinally interesting pyrazolone derivatives in good to excellent yields of 51–98% under microwave irradiation and solvent-free conditions has been developed.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.