An efficient monitoring technique for solid-phase reactions by KBr pellets/FT-IR using methyl p-aminobenzoate synthesis assisted by microwave radiation on merrifield resin

Journal of the Brazilian Chemical Society

Dyeison Antonow²  Cedric Stephan Graebin¹  Vera Lucia Eifler-lima¹ 

[1] ,Universidade Federal do Rio Grande do Sul Faculdade de Farmácia Porto Alegre RS ,Brazil

关键词: Merrifield resin;    infrared spectroscopy;    solid phase organic synthesis;    microwave-assisted reactions;   

DOI  :  10.1590/S0103-50532004000500028

来源: SciELO

【 摘 要 】

The use of KBr pellets in infrared spectroscopy has been investigated for monitoring solid-phase reactions. Synthesis of the methyl p-aminobenzoate on Merrifield resin (MR) is described as a model for this technique, which allows the progress of its three on-bead reaction steps to be monitored throughout their duration.

【 授权许可】

CC BY   
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