Synthesis and characterization of a linker for primary amines used in the solid phase organic synthesis of spermidine

Journal of the Brazilian Chemical Society

Aix-Marseille Université Spectropôle, Marseille, France¹  Aix-Marseille Université, Marseille, France¹  Ziarelli, Fabio¹  Lima, Edson L. S.¹  Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil¹  Caldarelli, Stefano¹  Gil, Rosane A. S. San¹  Silva, Emerson T. da¹ 

关键词: polyamines;    13C CPMAS NMR;    HRMAS NMR;    solid phase organic synthesis;    spermidine;   

DOI  :  10.1590/S0103-50532011000100011

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

A linker resin for the synthesis of functionalized spermidine in good yield is described, along with its characterization by infrared (IR), 13C solid-state nuclear magnetic resonance with cross polarization and magic angle spinning (13C CPMAS NMR) and 1H high resolution magic angle spinning nuclear magnetic resonance (1H HRMAS NMR. This linker has been regenerated after cleavage of spermidine and re-used without loss of efficiency.

【 授权许可】

Unknown