Nutritional status, metabolic changes and white blood cells in adolescents

Revista Paulista de Pediatria

Thatianne Moreira Silva Oliveira¹  Franciane Rocha De Faria¹  Eliane Rodrigues De Faria¹  Patrícia Feliciano Pereira¹  Sylvia C.c. Franceschini¹  Silvia Eloiza Priore¹ 

关键词: Obesity;    Adolescent;    Risk factors;    Leukocyte count;    Obesidade;    Adolescente;    Fatores de risco;    Contagem de leucócitos;   

DOI  :  10.1590/S0103-05822014000400011

来源: SciELO

【 摘 要 】

OBJECTIVE: To analyze the relationship between the peripheral blood white cells, metabolic changes, and nutritional status of adolescents with and without excess weight and body fat.METHODS: This cross-sectional study evaluated the body mass index (BMI) and percentage body fat (%BF) in 362 adolescents from 15 to 19 years of age, of both sexes. White blood cell count, platelet count, uric acid, fasting glucose, insulin, and lipid profile were measured. The inclusion criteria were agreement to participate in the study and signature of the informed consent. Exclusion criteria were: presence of chronic or infectious disease; use of medications that could cause changes in biochemical tests; pregnancy; participation in weight reduction and weight control programs; use of diuretics and laxatives; or the presence of a pacemaker. The following statistical tests were applied: Kolmogorov-Smirnov test, Student's t or Mann-Whitney test, Pearson or Spearman correlation tests, and chi-squared test, considering p<0.05.RESULTS: Overweight was observed in 20.7% of adolescents. The total cholesterol (TC) had a higher percentage of inadequacy (52.2%), followed by high-density lipoprotein (HDL) (38.4%). There was a positive correlation between white cells and serum lipids, insulin, body fat, and BMI. Monocytes were negatively correlated with BMI, and rods with BMI, body fat, and insulin.CONCLUSIONS: Nutritional status is related to an inflammatory process, and adolescents with excess weight or body fat presented higher amounts of white blood cells.

【 授权许可】

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