Acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigs

Acta Cirurgica Brasileira

Apóstolo Ferreira Martins¹  Naida Cristina Borges¹  Priscila Vaz Coutinho¹  Aline Rodrigues Lemes¹  Ashbel Schneider Da Silva¹  Rayssa Kossa Barbosa¹  Neusa Margarida Paulo¹ 

关键词: Chitosan;    Peritoneum;    Surgical Mesh;    Swine;   

DOI  :  10.1590/S0102-865020150100000004

来源: SciELO

【 摘 要 】

PURPOSE: To assess the systemic response of pigs to the intraperitoneal implantation of polypropylene mesh associated with chitosan-based film with a degree of deacetylation of 95%.METHODS: Blood samples were collected 24 hours before, and two and seven days after surgery. Systemic reactions were evaluated based on white blood cell count, C-reactive protein, and total serum protein, albumin and globulin levels.RESULTS: The systemic response was proportional to the composite response induced by polypropylene mesh, and the tissue inflammatory response was higher in the PP group (p=0.0033).CONCLUSION: The polypropylene mesh/chitosan-based film composite did not elicit a systemic response in pigs.

【 授权许可】

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