Identification of risk factors for death from tetanus in Pernambuco, Brazil: a case-control study

Revista do Instituto de Medicina Tropical de São Paulo

Demócrito B. Miranda-filho¹  Ricardo A.a. Ximenes²  Silvya N. Bernardino²  Abelardo G. EscariÃo² 

[1] ,Universidade de Pernambuco Faculdade de Ciências Médicas Recife PE ,Brasil

关键词: Tetanus;    Death from tetanus;    Risk factors;    Disease progression;    Case-control;   

DOI  :  10.1590/S0036-46652000000600006

来源: SciELO

【 摘 要 】

A case-control study was conducted to identify risk factors for death from tetanus in the State of Pernambuco, Brazil. Information was obtained from medical records of 152 cases and 152 controls, admitted to the tetanus unit in the State University Hospital, in Recife, from 1990 to 1995. Variables were grouped in three different sets. Crude and adjusted odds ratios, p-values and 95% confidence intervals were estimated. Variables selected in the multivariate analysis in each set were controlled for the effect of those selected in the others. All factors related to the disease progression - incubation period, time elapsed between the occurrence of the first tetanus symptom and admission, and period of onset - showed a statistically significant association with death from tetanus. Similarly, signs and/or symptoms occurring on admission or in the following 24 hours (second set): reflex spasms, neck stiffness, respiratory signs/symptoms and respiratory failure requiring artificial ventilation (third set) were associated with death from tetanus even when adjusted for the effect of the others.

【 授权许可】

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